4,698 research outputs found

    Rethinking the Role of Recourse in the Sale of Financial Assets

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    The presence of recourse in the sale of a financial asset is generally thought to jeopardize the true sale treatment of the sale, especially in the event of the seller\u27s bankruptcy. This article examines the existing law and concludes that a transfer that qualifies as a sale under state law should be treated as a sale even if the buyer retains recourse to the seller, so long as recourse is limited to warranting that the asset will perform in accordance with its terms

    Sustainable Recycling of Insoluble Rust Waste for the Synthesis of Iron-Containing Perovskite-Type Catalysts

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    Insoluble rust waste from the scraping of rusted iron-containing materials represents a cheap, eco-friendly, and available source of iron. LaFeO3 perovskite-type powders were successfully prepared by solution combustion synthesis using rust waste from an electricity transmission tower manufacturer. Solution combustion synthesis enabled introduction of this insoluble iron precursor directly into the final product, bypassing complex extraction procedures. Catalytic activity in the propylene oxidation of the waste-derived LaFeO3 with stoichiometric Fe/La ratio was almost identical to the commercial iron nitrate-derived LaFeO3 , thus demonstrating the viability of this recycling solution. The amount of waste iron precursor was varied and its effect on the powder properties was investigated. A lesser stoichiometric amount of precursor produced a LaFeO3 -La2O3 binary system, whereas a higher stoichiometric amount led to a LaFeO3 -Fe2O3 binary system. Catalytic activity of iron-rich compositions in the propylene oxidation was only slightly lower than the stoichiometric one, whereas iron-poor compositions were much less active. This eco-friendly methodology can be easily extended to other iron perovskites with different chemical compositions and to other iron-containing compounds

    Synchrotron oscillation damping due to beam-beam collisions

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    In DA{\Phi}NE, the Frascati e+/e- collider, the crab waist collision scheme has been successfully implemented in 2008 and 2009. During the collision operations for Siddharta experiment, an unusual synchrotron damping effect has been observed. Indeed, with the longitudinal feedback switched off, the positron beam becomes unstable with beam currents in the order of 200-300 mA. The longitudinal instability is damped by bringing the positron beam in collision with a high current electron beam (~2A). Besides, we have observed a shift of \approx 600Hz in the residual synchrotron sidebands. Precise measurements have been performed by using both a commercial spectrum analyzer and the diagnostics capabilities of the DA{\Phi}NE longitudinal bunch-by-bunch feedback. This damping effect has been observed in DA{\Phi}NE for the first time during collisions with the crab waist scheme. Our explanation is that beam collisions with a large crossing angle produce a longitudinal tune shift and a longitudinal tune spread, providing Landau damping of synchrotron oscillations.Comment: 3 pages, 5 figures, talk presented to IPAC'10 - Kyoto - May 24-28 201

    Public crowdsensing of heat waves by social media data

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    Abstract. Investigating on society-related heat wave hazards is a global issue concerning the people health. In the last two decades, Europe experienced several severe heat wave episodes with catastrophic effects in term of human mortality (2003, 2010 and 2015). Recent climate investigations confirm that this threat will represent a key issue for the resiliency of urban communities in next decades. Several important mitigation actions (Heat-Health Action Plans) against heat hazards have been already implemented in some WHO (World Health Organization) European region member states to encourage preparedness and response to extreme heat events. Nowadays, social media (SM) offer new opportunities to indirectly measure the impact of heat waves on society. Using the crowdsensing concept, a micro-blogging platform like Twitter may be used as a distributed network of mobile sensors that react to external events by exchanging messages (tweets). This work presents a preliminary analysis of tweets related to heat waves that occurred in Italy in summer 2015. Using TwitterVigilance dashboard, developed by the University of Florence, a sample of tweets related to heat conditions was retrieved, stored and analyzed for main features. Significant associations between the daily increase in tweets and extreme temperatures were presented. The daily volume of Twitter users and messages revealed to be a valuable indicator of heat wave impact at the local level, in urban areas. Furthermore, with the help of Generalized Additive Model (GAM), the volume of tweets in certain locations has been used to estimate thresholds of local discomfort conditions. These city-specific thresholds are the result of dissimilar climatic conditions and risk cultures

    18F-FDG-PET/CT imaging in cardiac tumors: illustrative clinical cases and review of the literature.

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    Cardiac tumors are a very rare condition. Mostly, they are benign tumors (75%), with myxomas being the most frequent. The remaining 25% are malignant; either primary malignant sarcoma or secondary metastases. Given the small number of cases reported and the lack of prospective and randomized clinical trials, the level of evidence for the optimal multimodal treatment of primary cardiac sarcomas is very low and the optimal imaging diagnostic workup is not well established. In particular, 18F-FDG-PET/CT is not yet included in routine diagnosis of cardiac masses. Here, we report four illustrative clinical cases and a review of the literature on the current available data on the role of 18F-fluorodeoxyglucose PET/CT imaging in cardiac tumors

    A CD64/FcγRI-mediated mechanism hijacks PD-1 from PD-L1/2 interaction and enhances anti-PD-1 functional recovery of exhausted T cells.

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    Therapeutic monoclonal antibodies (mAb) targeting the immune checkpoint inhibitor programmed cell death protein 1 (PD-1) have achieved considerable clinical success in anti-cancer therapy through relieving T cell exhaustion. Blockade of PD-1 interaction with its ligands PD-L1 and PD-L2 is an important determinant in promoting the functional recovery of exhausted T cells. Here, we show that anti-PD-1 mAbs act through an alternative mechanism leading to the downregulation of PD-1 surface expression on memory CD4 <sup>+</sup> and CD8 <sup>+</sup> T cells. PD-1 receptor downregulation is a distinct process from receptor endocytosis and occurs in a CD14 <sup>+</sup> monocyte dependent manner with the CD64/Fcγ receptor I acting as the primary factor for this T cell extrinsic process. Importantly, downregulation of surface PD-1 strongly enhances antigen-specific functional recovery of exhausted PD-1 <sup>+</sup> CD8 <sup>+</sup> T cells. Our study demonstrates a novel mechanism for reducing cell surface levels of PD-1 and limiting the inhibitory targeting by PD-L1/2 and thereby enhancing the efficacy of anti-PD-1 Ab in restoring T cell functionality

    An overview on molecular characterization of thymic tumors: Old and new targets for clinical advances

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    Thymic tumors are a group of rare mediastinal malignancies that include three different histological subtypes with completely different clinical behavior: the thymic carcinomas, the thymomas, and the rarest thymic neuroendocrine tumors. Nowadays, few therapeutic options are available for relapsed and refractory thymic tumors after a first-line platinum-based chemotherapy. In the last years, the deepening of knowledge on thymus’ biological characterization has opened possibilities for new treatment options. Several clinical trials have been conducted, the majority with disappointing results mainly due to inaccurate patient selection, but recently some encouraging results have been presented. In this review, we summarize the molecular alterations observed in thymic tumors, underlying the great biological differences among the different histology, and the promising targeted therapies for the future
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